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KMID : 1022820180090020047
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Journal of Multiple Sclerosis and Neuroimmunology
2018 Volume.9 No. 2 p.47 ~ p.50
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Idiopathic Relapsing and Remitting Myelitis
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Kim Ji-Ah
Park So-Hyun
Yoo Il-Han
Kim Yong-Sung
Ahn Suk-Won
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Abstract
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Acute transverse myelitis (ATM) is an acute inflammatory disease of the spinal cord, characterized by rapid onset of bilateral neurological symptoms involving weakness, sensory disturbance, and autonomic impairment over hours or days. Relapsing ATM has been reported in approximately 25-33% of patients with ATM. Recently, we treated a patient with 6 episodes of relapsing myelitis who had not been diagnosed with any specific etiology. A 48-year-old female visited the hospital with complaints of leg weakness and numbness in both hands for 4 days. She had no autoimmune disease, history of infection, or notable family history. Cervical spine MRI showed diffuse T2 high signal intensity in the spinal cord with enhancement, and she was treated with high doses of intravenous methylprednisolone. Unexpectedly, she experienced 6 courses of relapsing and remitting acute myelitis despite extensive immunotherapy. The etiology of relapsing myelitis is not certain in this case. Large clinical studies of disease entity, etiology, and guidelines of immunotreatment for patients with idiopathic relapsing myelitis are needed.
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KEYWORD
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Myelitis transverse, Acute relapsing multiple sclerosis, Multiple sclerosis
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